Impact of Maternal Factors on Vertical HIV Transmission in Jigawa State, Nigeria: A Multilevel Analysis of Antenatal Care and Knowledge of HIV Status
DOI:
https://doi.org/10.62054/ijdm/0201.19Keywords:
ANC, MTCT, intra class correlation, hierarchical regression, paediatricsAbstract
Human immunodeficiency virus (HIV) transmission from mother to child is responsible for over 90% of paediatric acquired immunodeficiency syndrome (AIDS), with Nigerian infants being the most susceptible in the global prevalence ladder. This is due to the prevalence of factors such as late enrolment to the follow-up clinic, rural residence, absence of maternal preventive measures for vertical transmission, and mixed infant feeding practices among HIV positive mothers. This study assessed the impact of mothers’ knowledge of their status, mode of infants feeding at birth, and their uptake of antenatal care (ANC) on Mother-to-child-Transmission (MTCT) of HIV; using data from five General hospitals and one specialist hospital in Jigawa State. A two-level hierarchical model is fitted and the intraclass correlation coefficient (ICC) computed for three (3) key predictor variables namely: Location, number of antenatal care visits, and mothers’ knowledge of their HIV/AIDS status so as to assess clustering structure. The study findings reveal that there exist a 63.4% correlation between the individual level factors and “Location”; ANC visits accounted for 25.9%, while Knowledge of HIV status returns an ICC of 73.8%. These findings show that the likelihood of a vertical transmission in the population is very much influenced by these clustering variables. Hence, proper understanding of MTCT should take into cognisance the impact of mothers’ knowledge of their statuses and other personal characteristics such as their place of residence and ANC uptake.
References
Abiodun O, Sotunsa J, Ani F, Olaleye, A., Taiwo, A. (2015). Elimination of Mother-To-Child Transmission
of HIV in Nigeria: The Roles, Preparedness and Determinants of Successful Involvement of
Traditional Birth Attendants. J AIDS Clin Res 6: 481. doi:10.4172/2155-6113.1000481.
Kassa, G.M. (2018). Mother-to-child transmission of HIV infection and its associated factors in Ethiopia:
A systematic review and meta-analysis. BMC Infect Dis, 10;18(1):216.
https://doi.org/10.1186/s12879-018-3126-5.
Koye, D.N. &Zeleke, B. M. (2013). Mother-to-child transmission of HIV and its predictors among HIV-
exposed infants at a PMTCT clinic in northwest Ethiopia. BMC Public Health, 13:398.
http://www.biomedcentral.com/1471-2458/13/398.
NACA (2024). Preventing Mother-to-Child Transmission of HIV - NACA Nigeria
Olagunju, M., Jimoh, R.G. & Juhriyansyah, D. (2011). Predictive Control Model of HIV/AIDS Spread
With Emphasis in Nigeria, International Journal of Science and Advanced Technology , (ISSN
-8386) Vol.1 No.2, Retrieved March 2 2019 from http://www.ijsat.com
Terefe, B., Jembere M. M & Liyew, B. (2024). Comprehensive knowledge of mother-to child HIV/AIDS
transmission, prevention, and associated factors among reproductive age women in East Africa:
insights from recent demographic and national health surveys. BMC Women's Health 24:318
https://doi.org/10.1186/s12905-024-03173-1
UNAIDS (2021) Anambra, Nigeria, commits to eliminating vertical transmission of HIV by end of 2022 |UNAIDS
United Nations Programme on HIV/AIDS (UNAIDS) (2018). 90–90-90: An ambitious treatment target to
help end the AIDS epidemic Report. Geneva.
Waruru, A., Thomas N.O. A, Muttai, H, Ng’ang’a, L., Gutierrez, E.Z., Ochanda, B., Katana, B., Young,
P.W., Tobias, J.L., Juma, P. , Cock, K.M.D.& Tylleska, T. (2018). Spatial–temporal trend for
mother-to-child transmission of HIV up to infancy and during pre-Option B+ in western Kenya.
World Health Organization (2010). New data on the prevention of mother-to-child transmission of HIV and
their policy implications. Conclusions and recommendations. WHO technical consultation on
behalf of the UNFPA/UNICEF/WHO/ UNAIDS Inter-Agency Task Team on Mother-to-Child
Transmission of HIV.
World Health Organization (2018). Mother-to-child transmission of HIV.
http://www.who.int/hiv/topics/mtct/about/en/.
World Health Organization (2023) Epidemiological fact sheet: HIV statistics, globally and by WHO region.
Wudineh F. & Damtew, B. (2016). Mother-to-Child Transmission of HIV Infection and Its Determinants
among Exposed Infants on Care and Follow-Up in Dire Dawa City, Eastern Ethiopia. Hindawi
Publishing Corporation AIDS Research and Treatment Volume 2016, pp. 1 – 6.
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